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Up to 300 milligrams (mg) of allopurinol can be taken at one time. However, allopurinol did not cause birth defects or other problems in rats or rabbits given doses up to 20 times the amount usually given to humans. Do not use this medication if you are allergic to didanosine, or if you are also taking allopurinol (Zyloprim) or ribavirin (Rebetol, Ribasphere, Copegus Virazole). Allopurinol will not relieve a gout attack that has already started. You will need to discuss the benefits and risks of using Allopurinol while you are pregnant.
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